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Is aromatase inhibitor a steroid? Steroidal structure. Drugs like exemestane and other steroidal aromatase inhibitors have a steroidal structure that competes with the natural aromatase substrate androstenedione. Due to its selective inhibition it will not affect the production of the other steroids in the estrogen biosynthetic pathway.
Is exemestane liver toxic? Exemestane is metabolized in the liver and forms a number of metabolites, with little knowledge of their toxic potential. A series of events may have occurred to explain our patient's exemestane -induced severe cholestatic hepatitis.
Is hair loss from Arimidex permanent? Arimidex and Hair Loss : A Surprising Side Effect. And aromatase inhibitors (AIs: Aromasin, Arimidex, Femara) can cause joint and bone pain so severe that women stop taking them, more willing to risk a cancer recurrence than endure daily debilitating pain.
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