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Side products and by-products of the reaction and adjunct reagents used in the reaction will, in most cases, also be present in the product mixture.

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To measure the MMP and TIMP expression levels in HNPCECs in the present study, we did not use the ester prodrugs of latanoprost and tafluprost, but rather used the free acid forms to avoid differences in efficacy owing to hydrolysis by esterases.

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